Careers

About Aimm Therapeutics

AIMM Therapeutics BV is an Amsterdam based biotech company that develops human monoclonal antibodies for the treatment of cancer. AIMM was established fourteen years ago on the belief that scientists could harness the power of specific immune cells to develop clinically relevant antibody therapies while avoiding the inefficiencies inherent to other techniques. Today this proprietary platform technology is well validated as evidenced by the two AIMM antibodies now in human clinical trials and the deep pipeline that AIMM is currently advancing in cancer.

We have an opportunity for a highly motivated and experienced

Director Chemistry, Manufacturing and Controls (CMC)

    Requirements and Key responsibilities

  • Implement and lead the early development activities and build the required infrastructure with internal and external resources for a successful development of therapeutic antibody candidates including cell line development, process development, analytics and quality control, regulatory affairs and quality assurance
  • Preparation and execution of drug development plans spanning preclinical up to early clinical development for in-house programs
  • Selection and evaluation of CMOs and CROs and academic institutions, including contract negotiations, planning and monitoring of studies
  • Design of the GMP manufacturing plan for selected drug candidates and responsibility of the early development plan in accordance with Quality Assurance and Regulations
  • Lead the CMC activities including cell line development, manufacturing, toxicology, and regulatory issues
  • Design, plan, execute, interpret and communicate preclinical and early clinical programs on time, meeting identified objectives and within budget, in close collaboration with the management team
  • Coordinate with the scientific team and the development team to execute on development and implementation of IND-enabling activities
  • Ensure development projects are being performed in accordance with agreed-upon plans, budgets, timelines and under regulatory compliance
  • Participate in the evaluation of research programs and selection for research to development transition of discovery programs
  • Resources and budget responsibility for the activities and controlling Create and maintain an international network with external experts and key opinion leaders
  • Represent the company ́s development programs as needed as senior spokesperson externally e.g. at meetings with scientific advisors, consultants or at congresses
  • Keep up to date on scientific progress in the area of development and co-ordinate with various international Investigators
  • This position requires 25% travel
  • Candidate profile:

  • PhD in natural sciences
  • At least 8-year experience in an industry or CRO related to CMC development and regulatory
  • Experience in developing biologics
  • Experience in setting-up of the production processes of antibodies
  • Deep understanding of the preclinical and early clinical drug development process
  • Excellent communication skills in English
  • Ability to work in a small company environment

This fulltime position is located in Amsterdam, the Netherlands. Salary is commensurate with position and experience.

More information about the position can be obtained from AIMM’s CEO, John Womelsdorf (jwomelsdorf@aimmtherapeutics.com). Please send your application in English together with CV and names of preferably three references (including email address and phone number) before July 1, 2018 to: info@aimmtherapeutics.com, regular mail: AIMM Therapeutics BV, Meibergdreef 59, 1105 BA, Amsterdam.