Discovering therapeutic antibodies designed by nature

Strategic partnership with Cosmo Pharmaceuticals

AIMM Therapeutics in strategic partnership with Cosmo Pharmaceuticals

December 19, 2012

AIMM Therapeutics in strategic partnership with Cosmo Pharmaceuticals
 to combine Cosmo’s extended release technology & AIMM’s high quality antibodies to successfully combat gastrointestinal disease.

AIMM Therapeutics, a therapeutic antibody company, today announced a strategic partnership with Cosmo Pharmaceuticals (SIX:COPN), Milan, Italy, to develop oral diagnostic and therapeutic antibodies for gastrointestinal diseases including colon carcinoma. Under the agreement, Cosmo Pharmaceuticals will formulate novel human monoclonal antibodies generated by AIMM Therapeutics in an extended release form exploiting its proprietary MMX® technology. No financial details were disclosed.

Jan de Vries, CEO of AIMM Therapeutics, said, “The strong preclinical in vivo data generated by Cosmo using its MMX technology show the tremendous potential of oral antibody delivery for gastrointestinal diseases. We expect that the combination of Cosmo’s MMX technology with AIMM’s antibodies will allow us to build a unique portfolio of products with a compelling competitive advantage in gastrointestinal disease.” Mauro Ajani, Chairman and CEO of Cosmo Pharmaceuticals, said, “Access to AIMM’s proprietary high quality antibodies through our partnership will enable us to rapidly advance the oral delivery of diagnostic and therapeutic antibodies into clinical studies.‘’

About AIMM Therapeutics

AIMM Therapeutics (AIMM) is a leading antibody company that based on its synergistic, state-of-the-art antibody technology platform develops high affinity human monoclonal antibodies from immortalized and selected B cells of individuals who produce antibodies with high therapeutic value. AIMM antibodies can be further affinity matured in a proprietary process that does not require molecular engineering. AIMM has a broad product pipeline targeted at pathogenic viruses and bacteria, and is expanding its pipeline with drug candidates for cancer and inflammatory diseases. For more information:

About COSMO Pharmaceuticals

Cosmo is a specialty pharmaceutical company that aims to become a global leader in the field of optimized therapies for selected gastrointestinal and topically treated skin disorders. The company’s proprietary clinical development pipeline specifically addresses innovative treatments for IBD, such as Ulcerative Colitis and Crohn’s Disease, and Colon Infections. In addition, the Company is developing a diagnostic for the detection of colon cancer and a new chemical entity for topical skin treatment. Cosmo’s first marketed MMX® product is Lialda®/Mezavant®/Mesavancol®, a treatment for IBD that is licensed globally to Giuliani and Shire Limited. Cosmo’s proprietary MMX® technology is at the core of the Company’s product pipeline and was developed from its expertise in formulating and manufacturing gastrointestinal drugs for international clients at its Good Manufacturing Practice facilities in Lainate, Italy. The technology is designed to deliver active ingredients in a targeted manner in the intestines. For further information on Cosmo, please visit the Company’s website: